Introduction to clinical trials: lay-friendly video

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• Format Videos
• Language/s Bulgarian, čeština, Dansk, Deutsch, Eesti, English, Español, Français, Gaeilge, Ελληνικά, Italiano, Latviešu, Lietuvių, Malti, Magyar, Nederlands, Polski, Português, Română, Slovenčina, Suomi, Svenska
• Target Audience Self-directed learning
• EBM Stage 0 - Why EBM?
• Duration <5 mins
• Difficulty Introductory

Key Concepts addressed

• 3-3a Do the advantages outweigh the disadvantages for you?
• 2-1a Comparison groups should be similar
• 2-1d People should not know which treatment they get
• 3-2a Do the outcomes measured matter to you?
• 1-2e Comparisons are needed to identify treatment effects
• 1-2f Consider all of the relevant fair comparisons

Details

This 5-minute lay-friendly video was created by the European Communication on Research Awareness Needs (ECRAN) Project.  The animation is available in 23 languages and is aimed at a lay audience, or those with little knowledge about clinical trials. The ECRAN group have also produced a great powerpoint presentation explaining clinical trial for patients(15-minutes).

Enjoy the film and discover how Clinical Trials work today.

Clinical Research from ECRAN project on Vimeo.

About the video

The ECRAN video explains the following key aspects of clinical trials:

• The clinical trial protocol must be approved by an ethics committee, with independent experts and patients’ representatives
• Participants should be divided into similar groups which receive the treatments and control or placebo respectively
• Random allocation of participants to these groups
• Participants, carers and researchers should be blinded to treatment allocation
• Results should be replicated in other independent trials
• The benefits and risks of new treatments should be evaluated together

Common pitfalls:

• Placebos should not be used where there are effective treatments available
• Trials should include patients like those in whom the treatment would be used in real life
• Treatments should improve outcomes that are important to patients
• New treatments should be better than the current treatment, not just a placebo

Languages

The video is available in the following languages:

bg – български Fullscreen: Vimeo Download: mp4	en – English Fullscreen: Vimeo Download: mp4	lv – latviešu Fullscreen: Vimeo Download: mp4	ro – română Fullscreen: Vimeo Download: mp4
cs – čeština Fullscreen: Vimeo Download: mp4	es – español Fullscreen: Vimeo Download: mp4	hu – magyar Fullscreen: Vimeo Download: mp4	sk – slovenčina Fullscreen: Vimeo Download: mp4
da – dansk Fullscreen: Vimeo Download: mp4	fr – français Fullscreen: Vimeo Download: mp4	mt – Malti Fullscreen: Vimeo Download: mp4	sl – slovenščina Fullscreen: Vimeo Download: mp4
de – Deutsch Fullscreen: Vimeo Download: mp4	ga – Gaeilge Fullscreen: Vimeo Download: mp4	nl – Nederlands Fullscreen: Vimeo Download: mp4	fi – suomi Fullscreen: Vimeo Download: mp4
et – eesti Fullscreen: Vimeo Download: mp4	it – italiano Fullscreen: Vimeo Download: mp4	pl – polski Fullscreen: Vimeo Download: mp4	sv – svenska Fullscreen: Vimeo Download: mp4
el – ελληνικά Fullscreen: Vimeo Download: mp4	lt – lietuvių Fullscreen: Vimeo Download: mp4	pt – português Fullscreen: Vimeo Download: mp4

Synopsis

Back in 1747, James Lind had never heard about clinical trials!

Lind was a Scottish naval surgeon, and he found himself on a Royal Navy ship full of sailors sick with scurvy. His ideas revolutionised our understanding of how to test which treatment might work best. His work not only saved lives on his ship, but laid the foundation for modern clinical trials (randomised controlled trials) as we know them today.

Every year since 2005, The European Clinical Research Infrastructures Network (ECRIN) has celebrated The International Clinical Trials’ Day (ICTD) at or around the 20th of May (www.ecrin.org) in order to commemorate the day James Lind started his famous trial (www.jameslindlibrary.org). ECRAN and ECRIN urge others to take up the habit of celebrating the ICTD.