Surrogate Endpoints in EBM: What are the benefits and dangers?

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• Format Texts
• Language/s English
• Target Audience Further education
• EBM Stage 3 - Appraising evidence
• Duration <5 mins
• Difficulty Introductory

Key Concepts addressed

• 3-2a Do the outcomes measured matter to you?

Details

This article aims to emphasize the importance of assessing clinical trials that use surrogate outcomes very carefully before applying the recommended intervention into clinical practice. The blog explores the following questions: what are surrogate endpoints? What makes them so appealing to use in research (i.e. what are their benefits)? What are the dangers of their misuse? What determines whether using surrogate endpoints is the right approach to assess an intervention? Read the blog

Students 4 Best Evidence (S4BE) is a growing network of students from around the world, from school age to university, who are interested in learning more about evidence-based healthcare (EBH).  The network is supported by the UK Cochrane Centre.  In addition to the website, the S4BE has a Facebook group and Twitter feed. For more information, read Selena Ryan-Vigs blog which introduces Students 4 Best Evidence.