For lecture on 3 June 2021
University of Western Australia: Bias Minimisation, randomisation and blinding< Back to search results
- Format Texts
- Language/s English
- Target Audience Further education
- Difficulty Introductory
Key Concepts addressed
- 2-1a Comparison groups should be similar
- 2-1d People should not know which treatment they get
- 2-1g All should be followed up
- 3-2a Do the outcomes measured matter to you?
- 1-2f Consider all of the relevant fair comparisons
- 2-3f Confidence intervals should be reported
Bias minimisation; Study Methodology
- Randomisation eliminates investigator bias in allocating patients to different treatment arms.
- Blinding can avoid bias due to patient or observer knowledge of treatment allocation. Blinding can be through use of placebo or sham treatment. In a single blind study, only the patient or observer is unaware of the treatment allocation.