University of Western Australia: Bias Minimisation, randomisation and blinding

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  • Format Texts
  • Language/s English
  • Target Audience Further education
  • Difficulty Introductory

Key Concepts addressed


Bias minimisation; Study Methodology

  • Randomisation eliminates investigator bias in allocating patients to different treatment arms.
  • Blinding can avoid bias due to patient or observer knowledge of treatment allocation. Blinding can be through use of placebo or sham treatment. In a single blind study, only the patient or observer is unaware of the treatment allocation.

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