For lecture on 3 June 2021
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- Format Lessons, Websites
- Language/s English
- Target Audience Further education
- EBM Stage 3 - Appraising evidence
- Duration 5-15 mins
- Difficulty Intermediate
Key Concepts addressed
- 2-3d Fair comparisons with few people or outcome events can be misleading
- 2-3h Don’t confuse “no evidence” with “no effect”
A Web based Duke University. tutorial explaining how to address the question: How large was the treatment effect? What was the absolute risk reduction?
How large was the treatment effect? What was the absolute risk reduction?
Results: At 2 years, diabetes remission had occurred in none of the patients receiving medical therapy, as compared with 15 of 20 (75%) undergoing gastric bypass and 19 of 20 (95%) undergoing biliopancreatic diversion (P<0.001 for both comparisons). There was a significant association between study group and rate of remission. However, since there were no remissions in the medical-therapy group, risk ratios were computed in a more conservative fashion on the assumption that remission had occurred in the 2 patients in the medical-therapy group who dropped out. Read more